Researcher biography

Associate Professor Lutz Krause undertook undergraduate studies in Applied Computer science and completed his PhD in Bioinformatics and Genome Research in 2007 at Bielefeld University in Germany. During his graduate studies his primary research interests were in sequence analysis, metagenomics, machine-learning and development of efficient algorithms for next-generation sequencing. He also investigated the composition and function of natural microbial communities from diverse ecosystems, including biogas fermenters, coral reefs and waste water treatment plants. Lutz joined the Nestlé Research Center in Lausanne, Switzerland in 2008, where he studied the role of the gut microbiota in health and disease, in particular in obesity and diabetes. In 2010 he moved to Brisbane to take up the role as head of the Bioinformatics laboratory at the QIMR Berghofer Medical Research Institute. His team developed and applied bioinformatics methods in the context of biomedical research with a focus on the genetics and epigenetics of complex disorders and infectious diseases.

In 2014 Lutz joined the UQ Diamantina Institute to pursue his research on cancer genetics, biomarker discovery, genetics and epigenetics of complex diseases and parasite genomics. His group analyses heterogeneous data-sets, including copy-number variations, expression data, genomic mutations, structural variations and genome-wide methylation. In collaboration with the Princess Alexandra Hospital, Lutz research aims at the identification of biomarkers that help clinicians choosing the optimal treatment for individual OAC patients. In the field of infectious diseases, he is interested in discovering novel drug and vaccine targets against human parasites, based on the sequencing and comparative analysis of multiple parasite genomes. In collaboration with the Prince Charles Hospital our group is studying the genetics of lung cancer.